News Releases

Researchers Identify Genetic Mutation Linked to Congenital Heart Disease

Researchers Identify Genetic Mutation Linked to Congenital Heart Disease

Nationwide Children’s Hospital

A mutation in a gene crucial to normal heart development could play a role in some types of congenital heart disease—the most common birth defect in the U.S. The finding could help narrow the search for genes that contribute to this defect, which affects as many as 40,000 newborns a year.

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Rumors of male chromosome’s demise greatly exaggerated, study finds

Rumors of male chromosome’s demise greatly exaggerated, study finds

Whitehead Institute

The Y chromosome has seen its gene supply shrink from more than 1,000 genes when sex chromosomes first evolved, to what scientists once thought was only a handful of genes, a downward trend predicted to continue until the Y disappeared altogether. But two new studies suggest that the rumors of the Y’s demise have been greatly exaggerated.

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Study examines how cells tell each other apart

Study examines how cells tell each other apart

Whithead Institute

The idea of self vs. nonself may sound more like an existential identity crisis than a question in cellular biology. But to Whitehead Institute Associate Member Andrew Chess, the concept could offer information about how cells tell each other apart, a cellular self-awareness that ensures the correct wiring of neurons in the brain.

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Inactive genes may contribute to failure of animals cloned from adults cells, study finds

Inactive genes may contribute to failure of animals cloned from adults cells, study finds

Whitehead Institute

Only 1 percent to 3 percent of animals cloned from adult cells survive to birth; many die mysteriously very early in development, around the time of implantation. A new study suggests that a set of genes important in early development fails to reactivate in adult, or somatic, cell-derived clones, a finding that could help scientists skirt a major roadblock in cloning.

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Efforts to prevent childhood obesity must begin early

Efforts to prevent childhood obesity must begin early

Harvard Medical School

Efforts to prevent childhood obesity should begin far earlier than currently thought — perhaps even before birth — especially for minority children, according to a new study that tracked 1,826 women from pregnancy through their children’s first five years of life.

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